A supersoldier formula is invented. It's only effective on women. It drives men mad when it doesn't kill them outright.
Women are the weaker sex. That's not a moral judgment. That's if we just compare the average man to the average woman on a physical level. Let's leave aside any questions of spiritual or emotional strength or the long term ability to endure pain. Or just to endure. The average man is bigger and stronger than the average woman.
Now, what if there were a way to make women faster and stronger than men? What if the process only worked on women? How many women would take advantage of it? What kind of people would they become when a big man is no longer something to be afraid of?