A family of cannibals roams the freeways in an 18 wheel truck and trailer. They hunt their victims at rest stops and motels all across America.
For some reason the cannibal families in horror movies live on the outskirts of society. Physically as well as socially. They live off in the woods or the desert and wait for their food to come to them.
They must not be committed to their life style. If you want a steady supply of human meat you're more likely to find it where there's a lot of it. In cities. There are an unfortunate number of real life examples of people who managed to live in the city and eat a few fellow citizens before their neighbors finally noticed.
A better way to keep up the life style would be to stay on the move. Harvest your victims and sell their stuff in the next town down the road. Or, for greater anonymity, sell it on ebay.